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10 agosto, 2015 • 2:39 Enviado por SBI Comunicacao

Call for papers: Mediators of Inflammation

A Mediators of Inflammation, revista da Hindawi Publishing Group, está com call for papers aberto para sua edição especial sobre o papel de células residentes do sistema nervoso central na homeostase de tecidos e neuroinflamação. O número, que será publicado em abril de 2016, recebe manuscritos até o dia 27 de novembro. Veja a mensagem-convite da comissão editorial responsável pelo número – e confira, também, a íntegra do call for papers anexado abaixo:

Caros colegas,
                Nos
últimos anos temos acompanhado um crescimento significativo da área de
neuroimunologia. Cada vez mais tem sido aceito não só o conceito de que o
sistema nervoso tem a real capacidade de modular a resposta imune, mas também
de que células residentes, como células da micróglia, astrócitos e mesmo
neurônios participam ativamente da resposta imune em processos neuroinflamatórios.
A expressão de receptores para neurotransmissores em células imunes, linfócitos
T secretores de acetil-coina, a resposta anti-inflamatória vagal e mais
recentemente a descrição do sistema linfático do sistema nervoso, são alguns
desses exemplos. Nesse contexto, convido a todos a submeter artigos ou revisões
na área mencionada em um volume especial editado por mim juntamente com outros
pesquisadores.
                Aguardaremos
ansiosos.
Prof. Dr. Jean Pierre – ICB – USP
Profa. Dra. Carol Munhoz – ICB – USP

Prof. Dr. Dan Frenkel – Tel Aviv University

CALL FOR PAPERS: MEDIATORS OF INFLAMMATION
SPECIAL ISSUE ON THE ROLE OF CENTRAL NERVOUS SYSTEM RESIDENT CELLS IN TISSUE HOMEOSTASIS AND NEUROINFLAMMATION
Central nervous system resident glial cells, whose role was long described solely as both metabolic and structural supporters for neuronal function, have lately gained more and more attention from immunologists. In fact, besides their well-known importance in tissue homeostasis, astrocytes, microglial cells, and oligodendrocytes have also been described as important players during neuroinflammation. is is due to the capacity to secrete many important inflammatory mediators, as cytokines, chemokines, metaloproteinases, and many others, as well as through the capacity to directly interact with infiltrating inflammatory cells, as observed during antigen presentation to T lymphocytes. For instance, it is known that both astrocytes and microglial cells constitutively express the receptors for IFN- and IL-17, rendering them target for inltrating Th1 and Th17 cells, respectively. Thus, the importance of resident glial cells in the establishment and maintenance of the neuroinflammatory milieu has become unquestionable. However, there are still many gaps in the understanding of the interplay between resident glial cells and inflammatory leukocytes. In this context, researches in multiple sclerosis and its model, experimental autoimmune encephalomyelitis (EAE), had greatly contributed to a better view of the mechanisms involved. us, we invite researchers interested in spreading their findings in neuroimmunology and the role of glial cells in central nervous system inflammation to submit research as well as review articles for publication in this special issue of mediators of inflammation.

Potential topics include, but are not limited to:
  • Function and profile of cytokine secretion by glial cells
  • Role of pattern recognition receptors and inflammasome-related molecules in tissue inflammation
  • miRNA and glial cells
  • The dichotomy of M1/M2 microglia
  • Inflžammatory signalling pathways on glial cells
  • Cell-to-cell interaction of glial cells with central nervous system infiltrating leukocytes
  • Modulatory effect of glial-derived molecules
  • Cellular and molecular mechanisms of antigen presentation by glial cells to infiltrating lymphocytes
  • Role of glial cells on tissue repair
Authors can submit their manuscripts via the Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/rcns/.

Lead Guest Editor
Jean P. S. Peron, University of São Paulo,
São Paulo, Brazil
jeanpierre@usp.br

Guest Editors
Carolina D. Munhoz, University of São Paulo,
São Paulo, Brazil
cdmunhoz@usp.br

Dan Frenkel, Tel Aviv University,
Tel Aviv, Israel
dfrenkel@post.tau.ac.il

Manuscript Due
Friday, 27 November 2015

First Round of Reviews
Friday, 19 February 2016

Publication Date
Friday, 15 April 2016